Substance profile

Nicotine

What it is

Nicotine is a stimulant drug found naturally in the tobacco plant. It is the main addictive ingredient in cigarettes, cigars, and most vapes (e-cigarettes). It can also be found in products such as nicotine pouches and some chewing tobaccos. Although it is legal for adults, nicotine is one of the most addictive substances in common use.

How it affects you

Once inhaled or absorbed, nicotine reaches the brain within seconds. It triggers the release of dopamine, a chemical linked to pleasure and reward, which produces a short-lived feeling of relaxation or alertness. This effect fades quickly, which is part of why people reach for the next cigarette or vape so soon.

Why it is addictive

The brain quickly adapts to regular nicotine and starts to expect it. Dependence can build within weeks. When nicotine levels drop, withdrawal sets in — and the easiest way to relieve it is more nicotine, which keeps the cycle going. Common withdrawal symptoms include irritability, anxiety, restlessness, trouble concentrating, and strong cravings.

The risks

Signs it may be a problem

Where to get help (Australia)

Free and confidential support is available. You do not have to do this on your own.

Quitline Counselling and practical plans to quit smoking or vaping. 13 7848
National Alcohol & Other Drug Hotline Free, confidential advice and referrals, 24/7. 1800 250 015
Your GP / doctor Can advise on stop-smoking medications and support.
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